Research Associate/ Assistant in Bioinformatics

Department of Life Sciences

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Imperial College London, Exhibition Road, London, UK


  • Posted on: 15th Feb 2021
  • Salary: £36,045 - £48,340
  • REF: NAT00863
  • Closes: 15th March 2021
  • Contract Type: Fixed-Term/Contract
  • Hours: Full Time

Job description

Job summary

We are seeking to recruit a Research Assistant in the field of bioinformatics to work in a world-leading research group at the intersection of molecular biology and insect vector control. You will join the laboratory of Professor Andrea Crisanti based at the South Kensington Campus. Our research is based on cutting-edge molecular biology and genetics to understand and ultimately control the mosquito vectors of malaria. Our current focus is on the development of vector control strategies that are mainly based on gene drive systems. The projects typically involve generation of transgenic mosquito strains, genetic and phenotypic assays, mathematical modelling and multigenerational experiments to assess the effect and efficiency of the technology on caged populations.

Duties and responsibilities

As the dedicated bioinformatician for the group you will take initiatives in the planning of research and conduct data analysis. You will be required to maintain accurate and complete records of all findings and to provide bioinformatics assistance to Group members with Next-generation sequencing (NGS) data (e.g. RNA-Seq, scRNA-Seq, amplicon sequencing) from experiments with laboratory-reared mosquitoes and population genetics (e.g. individual genome re-sequencing) data. Based on input from researchers of the group, you will be able to execute suitable workflows and techniques to plan experiments for data collection, modelling and analyses. A key element of the role will be in helping to plan experiments in collaboration with wet lab researchers in order to ensure there is sufficient scientific power to answer the question at hand. A fundamental skill the applicant must possess is the ability to communicate their workflow and a breakdown of their analysis to a wide range of biologists that may not have a large amount of bioinformatics experience. You may also be required to collaborate with other allied scientists within Imperial College and elsewhere in London and abroad as appropriate.

Essential requirements

Research Assistant:

You must have an MSc (or equivalent) with good amount of experience in an appropriate biological science or computational discipline with a strong focus on bioinformatics, computational biology and genomics.

Research Associate

You must hold a PhD (or equivalent) in an appropriate biological science or computational discipline with a strong focus on bioinformatics, computational biology and genomics.

Experience with next generation sequencing analysis is essential. The successful candidate must have strong programming skills (preferably R and/or Python) and high working proficiency in a Unix/Linux environment. Experience with high-performance computing (HPC) is a plus.

A good knowledge of molecular biology, genomics, transcriptomics is highly desirable. Previous work experience in the field of insect biology is preferred, but not essential.

You must have excellent verbal and written communication skills. You must also be able to develop and apply new concepts and have a creative approach to problem-solving. The ideal candidate will have the passion and drive to tackle and overcome scientific problems.

Further information

This is a full time, 24-month fixed-term position with a possibility of extension.

*Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £36,045 – £39,183 per annum

For informal enquiries please contact Professor Andrea Crisanti (via ) or Dr Federica Bernardini ( )

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published.For more information, see

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level. /

Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.

Additional information

Please note that job descriptions cannot be exhaustive and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.

All Imperial employees are expected to follow the 7 principles of Imperial Expectations:

  • Champion a positive approach to change and opportunity
  • Communicate regularly and effectively within, and across, teams
  • Consider the thoughts and expectations of others
  • Deliver positive outcomes
  • Encourage inclusive participation and eliminate discrimination
  • Develop and grow skills and expertise
  • Work in a planned and managed way

In addition to the above, employees are required to observe and comply with all College policies and regulations.

We are committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment for all. We therefore encourage candidates to apply irrespective of age, disability, marriage or civil partnership status, pregnancy or maternity, race, religion and belief, gender identity, sex, or sexual orientation. We are an Athena SWAN Silver Award winner, a Disability Confident Leader and a Stonewall Diversity Champion.

For technical issues when applying online please email .

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