We seek to recruit and enthusiastic and highly motivated post-doctoral research associate to work in the lab of Dr Katie Doores in the Department of Infectious Diseases at King’s College London.
The post-doctoral research associate will use a combination of molecular, cellular and biochemical techniques to study the antibody response to SARS-CoV-2 infection and COVID-19 vaccination.
The successful candidate should be highly motivated and well organised, with experience in managing complex laboratory projects and communicating effectively with other scientists and students.
This is a full-time post, a fixed-term contract for 18 months.
- Perform antigen-specific B cell sorting to isolate SARS-CoV-2 specific monoclonal antibodies from infected and vaccinated individuals.
- To characterize monoclonal antibodies and serum samples using ELISA and cell-based neutralization assays.
- Viral glycoprotein and antibody production and purification.
The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.
Skills, knowledge, and experience
- PhD awarded in Immunology, Virology, Biochemistry or related Biomedical Science or PhD in Immunology, Virology, Biochemistry or related Biomedical Science near completion.
- Experience in tissue culture, working with both primary cells and cell lines.
- Experience in molecular biology techniques including cloning, single cell PCR.
- Experience in immunological techniques including ELISA.
- Excellent technical aptitude, adaptable and willingness to learn new skills, scientific concepts and scientific techniques
- A track record of publication in respected scientific journals.
- Excellent communication skills.
- Excellent time management and organizational skills.
- Ability to work independently and as part of a team.
- Experience in protein and antibody expression and purification.
- Knowledge of B cell biology and immunology
- Proven experience in flow cytometry and cell sorting
Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.
This post is subject to Occupational Health clearance.