Experimental Scientific Officer

Faculty of Medical Sciences

Newcastle University, Newcastle upon Tyne, UK


  • Posted on: 08th Feb 2021
  • Salary: £30,942 - £32,817 per annum
  • REF: 5460
  • Closes: 10th March 2021
  • Contract Type: Permanent
  • Hours: Full Time

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

Salary: £30,942 – £32,817 per annum

Closing Date: 10 March 2021

The Role

We seek to recruit a PhD-level quantitative microscopy staff scientist on an open ended contract. Youwill work with microscopy experts to bring quantitative fluorescence microscopy methods to a wide group of researchers and projects through training and collaboration. Youwill work across the Centre for Bacterial Cell Biology and the Faculty of Medical Bioimaging Facility to drive forward advanced high resolution single cell microscopy. Youwill collaborate with eukaryotic cell biology labs on quantitative bioimaging projects. Youwill take an active scientific role in collaborative projects, for example, developing new microscopy protocols and image analysis workflows.




Further information can be obtained by contacting Dr Seamus Holden (seamus.holden@newcastle.ac.uk) or Dr Henrik Strahl (h.strahl@newcastle.ac.uk)

Key Accountabilities

Youwill be jointly supervised by Dr Séamus Holden (advanced microscopy & bacterial cell biophysics) and Dr Henrik Strahl (advanced microscopy & bacterial cell biology) and will be responsible for:

  • Train and help staff perform quantitative live cell fluorescence microscopy: subcellular protein localization and tracking, TIRF microscopy, single molecule tracking
  • Quantitative image analysis of live cell microscopy data, including training staff, establishing image analysis workflows and assisting staff with image analysis on projects
  • Development of automated image acquisition workflows
  • Opportunity to lead on key imaging collaborations, e.g. as image analyst collaborator
  • Collaborating with multiple bacteriology labs on quantitative live cell bacterial microscopy and single molecule biology projects, including hands on collaborative projects anduser training/ mentoring
  • Quantitative bioimage analysis of microscopy data, including user training/ mentoring and through direct collaboration
  • Managing and running a new microscope for high performance bacterial imaging with TIRF, single molecule and microfluidics capabilities
  • Maintenance and user training for existing CBCB microscopes

The Person (Essential)

Knowledge, Skills and Experience

  • Expert in fluorescence microscopy, in at least one of the following areas: live cell single cell microscopy, TIRF microscopy, single molecule fluorescence microscopy (in vivo or in vitro)
  • Expert in quantitative image analysis
  • Proficient in automated image analysis via a common scripting language, eg Python, ImageJ scripting, MATLAB
  • Experience in supporting and training others

Attributes and Behaviour

  • Excellent interpersonal skills
  • Well organizsed, able to manage and prioritize multiple tasks


  • PhD in Quantitative Microscopy, Biophysics, Bioimage analysis or related field

Newcastle University is committed to being a fully inclusive Global University which actively recruits, supports and retains staff from all sectors of society. We value diversity as well as celebrate, support and thrive on the contributions of all our employees and the communities they represent.We are proud to be an equal opportunities employer and encourage applications from everybody, regardless of race, sex, ethnicity, religion, nationality, sexual orientation, age, disability, gender identity, marital status/civil partnership, pregnancy and maternity, as well as being open to flexible working practices.

Requisition ID: 5460

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