Faculty of Humanities & Social Sciences
We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.
Salary: £28,331 – £31,866 per annum
Closing Date: 1 March 2021
A post is available for an enthusiastic and highly motivated Research Assistant/Associate to join a multidisciplinary project working in the laboratories of Julia Hubbard and Heath Murray. This MRC-funded position is based at the Centre for Bacterial Cell Biology (CBCB) at Newcastle University.
The aims of this project are to develop cellular assays for identifying small molecules that inhibit the essential bacterial DNA replication initiator DnaA and to construct DnaA mutations in ESKAPE pathogens to validate DnaA as a target for drug discovery. Ideal applicants should be in possession of, or near finalisation of a PhD in a relevant field.
Information about the Faculty of Medical Sciences is available at: https://www.ncl.ac.uk/medicalsciences/
Information about the Centre for Bacterial Cell Biology (CBCB) is available at: www.ncl.ac.uk/cbcb/
This post is available on a full time, fixed term basis for the duration of 12 months.
For informal enquiries please contact Dr Julia Hubbard (Julia.firstname.lastname@example.org) or Professor Heath Murray (email@example.com).
- Assay development for identification and characterisation on compounds affecting the function of DnaA in bacterial cells and in-vitro.
- Generate and characterise mutants of DnaA in relevant pathogens, for example Staphylocccus aureus.
- Contributing to the drug design process.
- Independent planning and communication of experimental strategies.
- Perform statistical and data analyses to produce robust and reproducible data.
- Present results in peer-reviewed publications and at scientific conferences.
- Perform risk assessments and maintain safety laboratory records (e.g. COSHH) in consultation with academic staff.
- Contribute to laboratory meetings, e.g. problem solving, internal seminars, journal club presentations.
- Organise and assist in general laboratory duties, e.g. equipment maintenance, stores.
The Person (Essential)
Knowledge, Skills and Experience
- Capacity for original thought.
- Enthusiastic and hard working.
- Excellent oral communication and writing skills.
- Team-working skills.
- High level analytical skills.
- Commitment to continuing professional development.
- Good IT and computing skills.
- Ability to take an active role in determining the future directions of a research project.
- Expertise in contemporary molecular biology techniques.
- Expertise in recombinant protein expression in bacteria.
- Presentation of work at scientific meetings.
- Clear commitment to a career in research.
- Expertise in protein purification.
- Expertise in assay design and data analysis.
- Team-working skills within multidisciplinary research teams.
- Laboratory supervision of students (PhD, MSc, BSc).
Attributes and Behaviour
- Commitment to a career in research
- Able to work in a team environment
- Values and appreciates diversity
- Bachelor’s degree (or equivalent) in a relevant science subject – preferably biomedical (Assistant level).
- A PhD in the area of microbiology or bacterial molecular biology (Associate level). Candidates who have submitted their thesis will be considered for Research Assistant level, until the PhD has been awarded.
- Masters qualification in a relevant subject (Assistant level).
Newcastle University is committed to being a fully inclusive Global University which actively recruits, supports and retains staff from all sectors of society. We value diversity as well as celebrate, support and thrive on the contributions of all our employees and the communities they represent. We are proud to be an equal opportunities employer and encourage applications from everybody, regardless of race, sex, ethnicity, religion, nationality, sexual orientation, age, disability, gender identity, marital status/civil partnership, pregnancy and maternity, as well as being open to flexible working practices.
The University holds a silver Athena SWAN award in recognition of our good employment practices for the advancement of gender equality. The University also holds the HR Excellence in Research award for our work to support the career development of our researchers, and is a member of the Euraxess initiative supporting researchers in Europe.
Requisition ID: 5881