Oxford-Janssen Postdoctoral Fellow (Eye Project 2)
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, Oxford OX3 7FY.
Grade 7: £32,817 – £40,322 p.a.
We are seeking a highly motivated and proactive Postdoctoral Fellow to join Professor Christopher Buckley and Dr Srilakshmi Sharma at the Kennedy Institute, to work within the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences at the University of Oxford. This is a unique opportunity for an ambitious postdoctoral scientist with skills in human tissue biology to join clinicians, bioinformaticians, and fellow-scientists in cross-cutting multidisciplinary work. The post holder will be a member of a research group with responsibility for carrying out laboratory work in a multicentre program on ocular immunology with a particular focus on histology and imaging.
You will coordinate with other postdoctoral members of the ORBIT team in the execution of histology and imaging leading to functional analyses based upon bioinformatics data, as well as manage own academic research and administrative activities of the multidisciplinary group. The aim of this project is to map the cells involved in the human uveal tract that are responsible for uveitis. This involves project management between multiple centres, organisation, and co-ordination of projects in order to meet deadlines. You will use your experience of working with human tissue and a wide variety of methodological skills to develop to adapt scientific techniques and experimental protocols. You will develop ideas for generating research income and present detailed research proposals to senior researchers and assist in developing grant applications.
You must hold a PhD/DPhil (or near completion) in Immunology, Molecular Biology or a related discipline and have a broad range of immunology-focused laboratory methodological skills and have experience of bioinformatic analysis of patient cohort data sets, including bulk and single cell RNA seq and/or spatial transcriptomics. You must have expertise in multiplex imaging panel design and tissue biopsy staining using GE Cell Dive, or comparable technology and experience with analysis of inflammatory signalling pathways in situ or in vitro. Experience of independently managing a discrete area of a research project and experience of teaching and training is desirable.
This is a fixed-term, full time position until 15/12/2023.
Due to the nature of the research at the Kennedy Institute of Rheumatology, this job will require additional security pre-employment checks:
• A satisfactory basic Disclosure and Barring Service check
• University security screening (eg identity checks)
The closing date for this position is 12 noon on Friday 12 March 2021. You will be required to upload a CV and supporting statement as part of your online application.
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