Postdoctoral Research Associate
Laboratory of Cerebral Ischaemia, Investigative Medicine, Radcliffe Department of Medicine (RDM), John Radcliffe Hospital, Oxford, OX3 9DU
Grade 7: £33,309 – £40,927 p.a
As our Postdoctoral Research Associate in circadian entrained in vitro models of Stroke you will be based at the Laboratory of Cerebral Ischaemia, John Radcliffe Hospital, Oxford. You will become an integral part of an interdisciplinary team working on elucidating the interplay between cerebral ischaemic injury and circadian pathways to uncover potential novel neuroprotective strategies. You will be developing novel microfluidic in vitro models of stroke to incorporate circadian rhythms and study their influence on ischaemic injury pathways in human cells. This will require experience with the development and use of microfluidic “Organ on Chip” models of the blood brain barrier and neuronal circuits along with an understanding of stroke and circadian biology.
This work is part of a larger consortium of researchers from leading research institutes around the world (Harvard, Stanford, UCLA, Complutense University of Madrid, University of Munich, Garvan Institute of Medical Research and University of Tasmania) focused on the study of circadian influence on stroke outcome from fundamental biology to clinical and population studies. You will act as a key member of the Oxford arm of this multidisciplinary team, co-ordinating in vitro studies between the labs of Professors Alastair Buchan, Russell Foster and David Ray whilst also fostering and maintaining international collaborations with the larger Leducq programme members.
You must hold a relevant PhD/DPhil (neuroscience, circadian biology, stroke biology or Organ on chip models). You will have knowledge, experience, and technical proficiency in designing developing and using microfluidic in vitro ‘Organ on chip’ models. Specific experience with developing and use of advanced in vitro stroke models or models of neurological disease is desirable.
The post is full time and fixed-term for 18 months in the first instance (with possible 18 months extensions up to 5 years).
Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application.
Only applications received before 12:00 midday on 23 November 2021 will be considered.
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