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Research Assistant: lymphatic vessel-immunomodulation following heart injury

Physiology Anatomy And Genetics

University of Oxford, Oxford, UK


  • Posted on: 15th Sep 2021
  • Salary: Grade 6: £29.614-£35.326 p.a.
  • REF: 153328
  • Closes: 18th October 2021
  • Contract Type: Fixed-Term/Contract
  • Hours: Full Time

Job Details

Research Assistant: lymphatic vessel-immunomodulation following heart injury

Sherrington Building, Department of Physiology, Anatomy and Genetics, Parks Road, Oxford, OX1 3PT

Grade 6: £29.614-£35.326 p.a.

Full time, fixed term post

Applications are invited for a Research Assistant to work with Professor Paul Riley on a Medical Research Council-funded programme of research, in which the overarching goal is to understand how the cardiac lymphatic vasculature can be fully exploited to modulate the immune response and optimize outcome after cardiac injury.

The successful applicant will work closely with two post-doctoral scientists and a senior research assistant on the same MRC-funded programme, focusing on the two major aims to define which immune cell sub-populations are beneficial or detrimental for improved outcome and modelling human lymphangiogenesis for drug discovery following heart attack (myocardial infarction).

Responsibilities will include learning and performing animal surgery to provide the relevant disease models and contributing to cell and tissue culture, histology, imaging and other experimental techniques relevant to the MRC programme and projects in the wider laboratory. You will be required to use specialist scientific equipment in a laboratory environment, and to contribution to other on-going research projects within the laboratory, in accordance with experience and grade. In addition, you will teach experimental techniques to graduate and undergraduate project students and providing supervision of these students within the laboratory and you will be expected to present at internal group meetings and have an opportunity to present at external scientific meetings and contribute to drafting manuscripts for the publication of the programme studies.

You will hold, a relevant BSc degree, and have experience in molecular/cellular biology relevant to the programme of work. You must be strongly motivated with a highly enthusiastic approach to science with good organizational, verbal, communication and interpersonal skills. You must be able to work both independently and part of a research team, and be capable of obtaining a Home Office personal license if you do not already hold one.

It is desirable (but not essential) that you have experience in cardiovascular research working with animal models, including surgical models. Experience of standard molecular cloning (recombineering), cell and tissue culture and confocal microscopy with image analysis software would be beneficial.

You will be based in the Sherrington Building, Department of Physiology, Anatomy and Genetics, Parks Road, Oxford, OX1 3PT.

The position is fixed term for 3 years, funded by the Medical Research Council.

Closing date for applications is Monday 18th October at 12noon.

Interviews are likely to be held week commencing 27th October.

Contact Person :

Danielle Grant

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Contact Phone :

Closing Date & Time :

18-Oct-2021 12:00

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