Research Associate – Molecular Pathogenesis of Parkinson’s Disease

Clinical Neurosciences

University of Oxford, Oxford, UK

Overview

  • Posted on: 26th Jan 2021
  • Salary: Grade 7: £32,817 - £40,322 per annum A less experienced candidate may be appointed at Grade 6 (£29,176 - £34,804 p.a.) with a commensurate adjustment in essential criteria, responsibilities and duties
  • REF: 149177
  • Closes: 02nd March 2021
  • Contract Type: Fixed-Term/Contract
  • Hours: Full Time

Job Details

Research Associate – Molecular Pathogenesis of Parkinson’s Disease

Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford

Grade 7: £32,817 – £40,322 per annum A less experienced candidate may be appointed at Grade 6 (£29,176 – £34,804 p.a.) with a commensurate adjustment in essential criteria, responsibilities and duties

We are seeking an ambitious and highly motivated post-doctoral scientist to work in a programme of research that aims to investigate novel drug targets in alpha-synuclein pathobiology. The study will involve the study of iPSC-based models using CRISPR/Cas9. Ad such the post will offer an excellent opportunity for mechanistic research and drug target identification in Parkinson’s disease using state-of-the-art models and facilities at the Nuffield Department of Clinical Neurosciences at the University of Oxford.

The post-holder will also benefit from and be exposed to interactions with Industry and work alongside a multidisciplinary team in the Molecular Neurodegeneration Research Group. They will use established lab protocols to differentiate iPSC into neurons and analyse scientific data to test new hypotheses and generate new constructs relevant to the project using CRISPR.

It is essential that the successful candidate hold or be nearing completion of a PhD/DPhil and they have a proven track record in cell culture, ideally iPSC-based models and imaging. It is also crucial that they have previous use of biochemical techniques in mechanistic studies and have a proven track record in molecular biology.

It would be beneficial to the role if the postholder had knowledge of proteostasis pathways and had experience in modelling of protein aggregation. It would also be beneficial if they had previous experience in models of Neurodegeneration.

The post is full-time for a fixed-term of 12 months in the first instance.

Only applications received before 12.00 midday on 2nd March 2021 will be considered.

Interviews will be held as soon as possible thereafter.

Contact Person :

Recruitment Team

Vacancy ID :

149177

Contact Phone :

Closing Date & Time :

02-Mar-2021 12:00

Contact Email :

recruitment@ndcn.ox.ac.uk

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