Research Fellow

Great Ormond Street Institute of Child Health

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UCL, Gower Street, London, UK


  • Posted on: 24th Nov 2021
  • Salary: £36,770 - £44,388 per annum
  • REF: 1880653
  • Closes: 15th December 2021
  • Contract Type: Fixed-Term/Contract
  • Hours: Full Time

Duties and Responsibilities

Professor Manju Kurian heads a dynamic research group within Molecular Neurosciences (Developmental Neurosciences Programme) at the UCL-Institute of Child Health. Her research group, based at the state-of-the art Zayed Centre for Research, has a strong interest in gene discovery, elucidating the biological processes underpinning disease, and using laboratory models to develop novel precision therapies for patients with childhood-onset neurological disorders (Nature Communications 2015, Nature Communications 2016, Nature Genetics 2017, American Journal of Human Genetics 2019, Annals of Neurology 2020, Brain 2020, Brain 2021, Science Translational Medicine 2021, The Lancet Neurology 2021 ). Her lab is currently funded through an NIHR Professorship, as well as the Sir Jules Thorn Award for Biomedical Research and a number of other project grants and personal fellowships from national research councils and charities.

We are seeking to appoint an enthusiastic Research Fellow to take part in a research project investigating human induced pluripotent stem cell (PSCs) derived neuronal models of childhood-onset movement disorders and epilepsy. Their main duties would involve the differentiation and maintenance of PSC-derived neurons, as well as the elucidation of disease mechanisms with standard laboratory techniques (qRT-PCR, Western blotting, confocal microscopy etc). This post will offer the successful candidate a unique opportunity to work in an exceptional and stimulating working environment in an extremely prestigious research centre and learn pioneering neuronal differentiation and disease modelling techniques, as well as the opportunity to lead in the contribution of work towards high-quality publications.

This post is available for 21 months in the first instance.

Key Requirements

PhD in a relevant field, High quality academic research with good working knowledge of methods mentioned in Job Description, Prior knowledge and extensive laboratory experience with stem cell culture and molecular biology techniques. Experience in maintenance and differentiation of PSCs and Background in working on monogenetic disease modelling, in particular, in vitro modelling with hiPSC-derived neurones are desirable.

Further Details

A job description and person specification can be accessed at the bottom of the page.

To apply for the vacancy please click on the Apply Now button below.

If you have any queries regarding the application process, please contact Madhur Sharma on quoting job reference 1880653.

UCL Taking Action for Equality

Closing Date

15 Dec 2021

Latest time for the submission of applications


Interview date


Our department holds an Athena SWAN Gold award, in recognition of our long-term commitment and ‘beacon’ status in advancing gender equality.

This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff.

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