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Research Fellows x2

UCL Queen Square Institute of Neurology

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UCL, Gower Street, London, UK

Overview

  • Posted on: 05th Nov 2021
  • Salary: £36,770 - £44,388 per annum
  • REF: 1879837
  • Closes: 21st November 2021
  • Contract Type: Fixed-Term/Contract
  • Hours: Full Time, Part Time

Duties and Responsibilities

Applications are invited for two Research Fellows to work with Prof Henry Houlden in the lab that is part of several world class initiatives which provide funding, including the MRC/NIHR funded genome sequencing program, Ataxia UK, the Wellcome Trust, The Multiple System Atrophy biomarkers project, the Sparks charity and a 5-year MRC International Centre for Neuromuscular Diseases. These are important international projects to work on developing DNA biomarkers in patient cohorts such as DRPLA and repeat expansion disorders (first post) and investigating genes associated with inherited disorders with a focus on channels and epilepsy, neurodegeneration and paroxysmal movement disorders using RNA/protein expression, tissue culture and oocyte expression systems (second post). Cutting edge genomic techniques will be used such as RNA and long-read sequencing, detailed genotype-phenotype studies and systems to investigate gene function already established in our laboratories.

The posts would be suited to different candidates with a combination of skills held by Research Fellows (neurology, paediatrics or clinical genetics), Post-Doctoral Fellows or Clinical Scientists. As well as cutting edge research, the posts will involve writing talks and working on publications and would suit highly motivated, ambitious, hardworking persons.

The posts are available immediately, with the first post being funded by a grant from GOSH to September 2022 in the first instance, and the second funded by a grant from the MRC to July 2022 in the first instance.

Key Requirements

The successful candidates must have an Honours degree (minimum 2:1) in Biological Sciences or a related discipline and a Degree in Medicine (MD, MBBS or similar) or higher degree in biological sciences or genetics or equivalent (PhD or similar). Clinical or genetic training in a number of different settings and experience of working with samples such as human blood and DNA are essential, as is knowledge of genetics and inherited rare (monogenic) diseases. Knowledge of the importance of understanding the international range of genetic variation in inherited diseases and a high level of consideration and care for patients and research subjects are also required. Experience of the clinical evaluation of children and/or adults with neurological disorders, and of bioinformatics analysis of high-throughput genetic data is desirable.

Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Research Assistant Grade 6B (salary 32,217 – 33,958 per annum including London Allowance) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.

Further Details

A Job Description and Person Specification can be accessed at the bottom of this page.

To apply for the vacancy, please click on the ‘Apply Now’ button below.

If you have any queries regarding the application process, please contact Oksana Shapoval, HR Officer, UCL Queen Square Institute of Neurology, 23 Queen Square, London, WC1N 3BG (email: ion.hradmin@ucl.ac.uk).

Potential applicants are welcome to contact Henry Houlden (h.houlden@ucl.ac.uk) for further information about the posts.

UCL Taking Action for Equality

We will consider applications to work on a part-time, flexible and job share basis wherever possible.

Closing Date

21 Nov 2021

Latest time for the submission of applications

23:59

Interview date

TBC

Our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality.

This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff.

Please use these links to find out more about UCL working life including the benefits we offer and UCL Terms and Conditions related to this job.

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